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Your Position: Accueil > Growth Hormone R

Growth Hormone R

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Cat . Non Espèces Description du produit Structure Pureté Caractéristique
GHR-H82F3 Human Biotinylated Human Growth Hormone R Protein, Fc,Avitag™ (MALS verified)
GHR-H82F3-structure
GHR-H82F3-sds
GHR-C52H1 Cynomolgus Cynomolgus Growth Hormone R (GHR) Protein, His Tag
GHR-C52H1-structure
GHR-C52H1-sds
GHR-R52H8 Rat Rat Growth Hormone R (GHR) Protein, His Tag
GHR-R52H8-structure
GHR-R52H8-sds
GHR-R52H9 Rabbit Rabbit Growth Hormone R (GHR) Protein, His Tag
GHR-R52H9-structure
GHR-R52H9-sds
GHR-C52H9 Canine Canine Growth Hormone R (GHR) Protein, His Tag
GHR-C52H9-structure
GHR-C52H9-sds
GHR-C5253 Rhesus macaque Rhesus macaque Growth Hormone R (GHR) Protein, Fc Tag
GHR-C5253-structure
GHR-C5253-sds
GHR-H8222 Human Biotinylated Human Growth Hormone R (GHR) Protein, His Tag, ultra sensitivity, primary amine labeling
GHR-H8222-structure
GHR-H8222-sds
GHR-H5257 Human Human Growth Hormone R (GHR) Protein, Fc Tag
GHR-H5257-structure
GHR-H5257-sds
GHR-H5222 Human Human Growth Hormone R (GHR) Protein, His Tag (MALS verified)
GHR-H5222-structure
GHR-H5222-sds
ACRO Quality

Part of Bioactivity data

GHR-C52H9-BLI
Growth Hormone R BLI

Loaded Canine Growth Hormone R, His Tag (Cat. No. GHR-C52H9) on HIS1K Biosensor, can bind Human GH, Tag Free with an affinity constant of 0.404 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
GHR-C52H1-ELISA
Growth Hormone R ELISA

Immobilized Human Growth Hormone Protein at 2 μg/mL (100 μL/well) can bind Cynomolgus Growth Hormone R, His Tag (Cat. No. GHR-C52H1) with a linear range of 0.6-39 ng/mL (QC tested).

Protocol

Synonym Name

GHR,GHBP,GH receptor

Background

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

Clinical and Translational Updates

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